2023 Volume 60 Issue 2 Pages 87-91
With the development of new drugs, such as molecular-targeted agents, and advances in medical technology, the number of cancer survivors is increasing every year. However, some anticancer drugs, particularly immune checkpoint inhibitors, have been found to cause potentially lethal cardiovascular dysfunction, and there is concern that this may affect the prognosis and quality of life of cancer patients. In addition, it has become clear that cancer itself and cancer cachexia, which occurs as cancer progresses, also cause cardiac dysfunction. Therefore, the prevention and treatment of cancer cachexia and cancer treatment-induced cardiac dysfunction are urgent issues. Exercise therapy has been reported to improve the prognosis of patients with chronic heart failure, as well as prevent the recurrence of cancer, and assists the completion of anticancer therapy in cancer patients. This review outlines the therapeutic effects of exercise therapy as a new treatment modality for cardiac dysfunction associated with cancer treatment, especially during cancer cachexia.
