1968 Volume 21 Issue 4 Pages 255-263
A new antibiotic, aristeromycin, was isolated from the culture filtrate of a new streptomyces, Streptomyces citricolor nov. sp. Aristeromycin is isolated using chromatography on active carbon, alumina and ion-exchange resin. Aristeromycin is isolated as colorless prism melting at 213-215°C (dec), and has the molecular formula C11H15O3N5. Its ultraviolet absorption maximum is observed at 262 mμ (El1%1cm 555). It shows inhibitory activities against Xantho monas oryzae and Piricularia oryzae in vitro as well as in vivo.