STUDIES ON TSUSHIMYCIN. I ISOLATION AND CHARACTERIZATION OF AN ACIDIC ACYLPEPTIDE CONTAINING A NEW FATTY ACID

JUN-ICHI SHOJI; SHUICHI KOZUKI; SABURO OKAMOTO; RYUJI SAKAZAKI; HIDEO OTSUKA

doi:10.7164/antibiotics.21.439

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

STUDIES ON TSUSHIMYCIN. I

ISOLATION AND CHARACTERIZATION OF AN ACIDIC ACYLPEPTIDE CONTAINING A NEW FATTY ACID

JUN-ICHI SHOJI, SHUICHI KOZUKI, SABURO OKAMOTO, RYUJI SAKAZAKI, HIDEO OTSUKA

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1968 Volume 21 Issue 7 Pages 439-443

DOI https://doi.org/10.7164/antibiotics.21.439

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Abstract

A new antibiotic, tsushimycin, was isolated from cultures of a Streptomyces strain. The antibiotic is an acidic acylpeptide related to the amphomycinglumamycin group of antibiotics. However, fatty acid analysis by means of gas-liquid chromatography revealed that the antibiotic contains isotetradecenoic acid which has not been found in known antibiotics. The constituent fatty acids as well as the amino acid composition were compared with those of the above group of antibiotics.

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