1969 Volume 22 Issue 10 Pages 457-462
Aabomycin A is a new antifungal antibiotic produced by a hitherto unidentified species of the genus Streptomyces. The active substance in fermented mash may be purified by solvent extraction followed by the chromatography on alumina column and then crystallization. Aabomycin A is easily soluble in many organic solvents, but is insoluble in water. It exhibits inhibitory activity against many fungi, especially against Piricularia oryzae, and has limited antiviral activity. The toxicity of aabomycin A for higher plants and animals is very low. Aabomycin A is similar in some properties to a few known antifungal antibiotics but differs from them in certain special characteristics.
