A NEW ANTIBIOTIC, HONDAMYCIN. III

CHEMICAL STUDIES ON HQNDAMYCIN. I

Abstract

The oxidation and alkaline degradation of the antibiotic hondamycin (C₄₇H₇₈O₁₃) give a tentative identification of the various functional groups.Evidence for an α, β-unsaturated ester group was obtained from ultraviolet, infrared and nuclear magnetic resonance spectra. Catalytic hydrogenation resulted in the reduction of four double bonds.