The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
VERMICULINE, A NEW ANTIPROTOZOAL ANTIBIOTIC FROM PENICILLIUM VERMICULATUM
J. FUSKAP. NEMECI. KUHR
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1972 Volume 25 Issue 4 Pages 208-211

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Abstract

A new crystalline antibiotic named vermiculine has been isolated from the fermentation broth of Penicillium vermiculatum DANGEARD. Vermiculine is a neutral colorless substance melting at 175-177°C with decomposition, containing only C, H and O. (λmax. 222mμ in methanol). The antibiotic inhibits growth of Trypanosoma cruzi, Leishmania braziliensis and some Grampositive bacteria.

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© Japan Antibiotics Research Association
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