The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
STUDIES ON A NEW AMINO ACID ANTIBIOTIC, AMICLENOMYCIN
YOSHIRO OKAMI, TAKEJI KITAHARA, MASA HAMADA, HIROSHI NAGANAWA, SHINICHI KONDO, KENJI MAEDA, TOMIO TAKEUCHI, HAMAO UMEZAWA
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1974 Volume 27 Issue 9 Pages 656-664

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Abstract

A new amino acid antibiotic, amiclenomycin is produced by Streptomyces lavendulae subsp. amiclenomycini OKAMI. The chemical structure of amiclenomycin is L-2-amino-4-(4'-amino-2', 5'-cyclohexadienyl)-butyric acid. The antibiotic inhibits growth of mycobacteria and this activity is reversed by biotin and desthiobiotin. α-Methyl-desthiobiotin is coproduced along with amiclenomycin.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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