A NEW ANTIBIOTIC, FUMARAMIDMYCIN I. PRODUCTION, BIOLOGICAL PROPERTIES AND CHARACTERIZATION OF PRODUCER STRAIN

HIROMI B. MARUYAMA; YASUJI SUHARA; JUNKO SUZUKI-WATANABE; YOSHIFUMI MAESHIMA; NOBUKO SHIMIZU; MICHIKO OGURA-HAMADA; HIDEO FUJIMOTO; KOUICHI TAKANO

doi:10.7164/antibiotics.28.636

A NEW ANTIBIOTIC, FUMARAMIDMYCIN

I. PRODUCTION, BIOLOGICAL PROPERTIES AND CHARACTERIZATION OF PRODUCER STRAIN

HIROMI B. MARUYAMA, YASUJI SUHARA, JUNKO SUZUKI-WATANABE, YOSHIFUMI MAESHIMA, NOBUKO SHIMIZU, MICHIKO OGURA-HAMADA, HIDEO FUJIMOTO, KOUICHI TAKANO

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JOURNAL FREE ACCESS

1975 Volume 28 Issue 9 Pages 636-647

DOI https://doi.org/10.7164/antibiotics.28.636

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Abstract

A new antibiotic, fumaramidmycin, has been isolated from a streptomycete NR-7GGl which was characterized and named Streptomyces kurssanovii. The strain produced the antibiotic only when grown on agar plates but not in the submerged culture broth, where the contact with the vegetative mycelia appears to cause the inactivation of the antibiotic. The antibiotic shows an antimicrobial activity against both Gram-positive and Gram-negative bacteria.

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