PLATOMYCINS A AND B I TAXONOMY OF THE PRODUCING STRAIN AND PRODUCTION, ISOLATION AND BIOLOGICAL PROPERTIES OF PLATOMYCINS

SEIGO TAKASAWA; ISAO KAWAMOTO; ITARU TAKAHASHI; MASAHIRO KOHAKURA; RYO OKACHI; SEIJI SATO; MITSUYOSHI YAMAMOTO; TOMOYASU SATO; TAKASHI NARA

doi:10.7164/antibiotics.28.656

PLATOMYCINS A AND B

I TAXONOMY OF THE PRODUCING STRAIN AND PRODUCTION, ISOLATION AND BIOLOGICAL PROPERTIES OF PLATOMYCINS

SEIGO TAKASAWA, ISAO KAWAMOTO, ITARU TAKAHASHI, MASAHIRO KOHAKURA, RYO OKACHI, SEIJI SATO, MITSUYOSHI YAMAMOTO, TOMOYASU SATO, TAKASHI NARA

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JOURNAL FREE ACCESS

1975 Volume 28 Issue 9 Pages 656-661

DOI https://doi.org/10.7164/antibiotics.28.656

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Abstract

Two new antibiotics. platomycins A and B. belonging to the phleomycin-bleomycin family, were isolated from the culture filtrate of Streptosporangium sp. MK-78. This strain has been identified as a new variety of Streptosporangium violaceochromogenes. Both platomycins A and B are active against a variety of Gram-positive and Gram-negative bacteria, and also inhibit solid Sarcoma 180 and EHRLICH ascites carcinoma.

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