The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
BIOTRANSFORMATION, A NEW APPROACH TO AMINOGLYCOSIDE BIOSYNTHESIS: II GENTAMICIN
R.T. TESTAB.C. TILLEY
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1976 Volume 29 Issue 2 Pages 140-146

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Abstract
Utilizing a paromamine-producing mutant of Micromonospora purpurea blocked in the production of gentamicin, bioconversion of various minor gentamicin components into the gentamicin C complex was demonstrated. The compounds tested Were structurally related to the gentamicin C's and are found as minor components in the gentamicin fermentation. Based upon the bioconversions detected, a branched pathway for the biosynthesis of the gentamicin C components is proposed.
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© Japan Antibiotics Research Association
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