THE STRIATINS-NEW ANTIBIOTICS FROM THE BASIDIOMYCETE CYATHUS STRIATUS (HUDS. ex PERS.) WILLD

Abstract

Three crystalline antibiotics which we named striatins A, B, and C were isolated from the mycelium of the basidiomycete Cyathus striatus strain No. 12. The striatins are highly active against fungi imperfecti and a variety of Gram-positive bacteria, as well as against some Gram-negative bacteria. The molecular formulas as determined by mass spectrometry are C₂₇H₃₆O₇ for striatin A, C₂₇H₃₆O₈ for striatin B, and C₂₅H₃₄O₇ for striatin C.