STRUCTURAL INVESTIGATION OF THE ANTIBIOTIC RISTOMYCIN A

¹³C-NMR SPECTRAL ANALYSIS OF THE INTERGLYCOSIDIC LINKAGES OF THE HETEROTETRASACCHARIDE SIDE-CHAIN

Abstract

By ¹³C-NMR studies on Ia, IIa, IIb and IVa obtained by the chemical degradation of
ristomycin A and on several synthetic model compounds it has been proved that an O-β-D-arabinopyranosyl-(1→2)-O-α-D-mannopyranosyl-(1→2)-O-[α-L-rhamnopyranosyl-(1→6)]-D-glucopyranosyl heterotetrasaccharide moiety is connected to the aglycone of the antibiotic.