A NEW BROAD-SPECTRUM AMINOGLYCOSIDE ANTIBIOTIC COMPLEX, SPORARICIN I. FERMENTATION, ISOLATION AND CHARACTERIZATION

TAKEO DEUSHI; AKIO IWASAKI; KAZUHIRO KAMIYA; TAKAFUMI KUNIEDA; TOSHIMI MIZOGUCHI; MASAHITO NAKAYAMA; HISAKATSU ITOH; TOSHIHITO MORI; TAKESHI ODA

doi:10.7164/antibiotics.32.173

A NEW BROAD-SPECTRUM AMINOGLYCOSIDE ANTIBIOTIC COMPLEX, SPORARICIN

I. FERMENTATION, ISOLATION AND CHARACTERIZATION

TAKEO DEUSHI, AKIO IWASAKI, KAZUHIRO KAMIYA, TAKAFUMI KUNIEDA, TOSHIMI MIZOGUCHI, MASAHITO NAKAYAMA, HISAKATSU ITOH, TOSHIHITO MORI, TAKESHI ODA

Author information

JOURNAL FREE ACCESS

1979 Volume 32 Issue 3 Pages 173

DOI https://doi.org/10.7164/antibiotics.32.173

Details

Abstract

Two new aminoglycoside antibiotics, sporaricins A (C₁₇H₃₅N₅O₅) and B (C₁₅H₃₂N₄O₄) produced by a rare actinomycetales, Saccharopolyspora hirsuta subsp. kobensis have been isolated by column chromatography on a cation-exchange resin. Sporaricin A is highly active against Gram-positive and Gram-negative bacteria including aminoglycoside-resistant strains.

Corresponding author

Register with J-STAGE for free!