The synthesis of a new penicillin, disodium D-6-[α-(1, 2, 4-triazine-3, 5-dione-6-carboxamido)-4-hydroxyphenylacetamido]penicillanate (BL-P1908), is described. The compound shows superior in vitro activity against Pseudomonas aeruginosa compared to carbenicillin and ticarcillin and produces higher intramuscular serum levels in mice than does carbenicillin.
