The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
MACBECINS I AND II, NEW ANTITUMOR ANTIBIOTICS
II. ISOLATION AND CHARACTERIZATION
MASAYUKI MUROI, MOTOWO IZAWA, YOSHIO KOSAI, MITSUKO ASAI
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JOURNAL FREE ACCESS

1980 Volume 33 Issue 2 Pages 205-212

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Abstract

New antitumor antibiotics, macbecins I and II, were isolated from the culture broth of Nocardia sp. No. C-14919. Macbecins I and II belong to the ansamycin group and have a benzoquinone and hydroquinone nucleus, respectively. Both showed antitumor activity against murine leukemia P 388 in vivo.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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