NEW ANTHRACYCLINONE METABOLITES FROM TWO BLOCKED MUTANTS OF STREPTOMYCES GALILAEUS MA144-M1αβ&

HIROYASU TORE; AKIHIRO YOSHIMOTO; TOMOYUKI ISHIKURA; HIROSHI NAGANAWA; TOMIO TAKEUCHI; HAMAO UMEZAWA

doi:10.7164/antibiotics.35.1641

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

NEW ANTHRACYCLINONE METABOLITES FROM TWO BLOCKED MUTANTS OF STREPTOMYCES GALILAEUS MA144-M1αβ&

HIROYASU TORE, AKIHIRO YOSHIMOTO, TOMOYUKI ISHIKURA, HIROSHI NAGANAWA, TOMIO TAKEUCHI, HAMAO UMEZAWA

Author information

JOURNAL FREE ACCESS

1982 Volume 35 Issue 12 Pages 1641-1645

DOI https://doi.org/10.7164/antibiotics.35.1641

Details

Abstract

Two blocked mutants of the aclacinomycin-producing Streptomyces galilaeus MA144-M1 produced new anthraquinones and anthracyclinones. The mutant ANR-58 produced compounds 58A, 58B, 58C (7-deoxy-2-hydroxyaklavinone), 58D (2-hydroxyaklavinone) and 58WR. All these compounds have the 2-hydroxyl group. The mutant ANR-665 produced compounds 665A and 665B. The compounds 58A, 58B and 665A have an anthraquinone skeleton.

Content from these authors

Favorites & Alerts

Corresponding author

Register with J-STAGE for free!