NEW ANTHRACYCLINE ANTIBIOTICS, AURAMYCINS AND SULFURMYCINS

I. ISOLATION AND CHARACTERIZATION OF AURAMYCINS A AND B, AND SULFURMYCINS A AND B

Abstract

Auramycins A and B and sulfurmycins A and B, new anthracycline antibiotics were discovered from the culture of a strain OBB-111, which was identified as Streptomyces galilaeus. The structures of the antibiotics were determined, indicating that auramycins and sulfurmycins are anthracycline glycosides of new aglycones designated auramycinone and sulfurmycinone.