THE TOTAL SYNTHESIS OF NOCARDICIN A

WILLIAM V. CURRAN; MARTIN L. SASSIVER; ADMA S. ROSS; THOMAS L. FIELDS; JAMES H. BOOTHE

doi:10.7164/antibiotics.35.329

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

THE TOTAL SYNTHESIS OF NOCARDICIN A

WILLIAM V. CURRAN, MARTIN L. SASSIVER, ADMA S. ROSS, THOMAS L. FIELDS, JAMES H. BOOTHE

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JOURNAL FREE ACCESS

1982 Volume 35 Issue 3 Pages 329-334

DOI https://doi.org/10.7164/antibiotics.35.329

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Abstract

We report here a total synthesis of nocardicin A. The antibiotic was obtained as a mixture of diastereoisomers that possessed approximately one quarter of the antibacterial activity of the naturally occurring material.

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