8006-I, AN ANTIBIOTIC FROM AMBLYOSPORIUM SPONGIOSUM (PERS.) HUGHES SENSU PIROZYNSKI I. TAXONOMY, FERMENTATION, ISOLATION AND PHYSICO-CHEMICAL PROPERTIES

G. RAK; H. ANKE; H. LAATSCH

doi:10.7164/antibiotics.35.431

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

8006-I, AN ANTIBIOTIC FROM AMBLYOSPORIUM SPONGIOSUM (PERS.) HUGHES SENSU PIROZYNSKI

I. TAXONOMY, FERMENTATION, ISOLATION AND PHYSICO-CHEMICAL PROPERTIES

G. RAK, H. ANKE, H. LAATSCH

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JOURNAL FREE ACCESS

1982 Volume 35 Issue 4 Pages 431-435

DOI https://doi.org/10.7164/antibiotics.35.431

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Abstract

A strain of Amblyosporium spongiosum (PERS.) Hughes sensu Pirozynski, HA 8006 isolated from an infected Lactarius deliciosus was found to produce two antibiotics, 8006-I and 8006-II. The same compounds could be isolated from cultures of several strains of the genus Amblyosporium obtained from the Centraalbureau voor Schimmelcultures. The highest yields of 8006-I (80 mg/liter culture) were obtained from the mycelium of strain HA 8006. Antibiotic 8006-I is unstable in the presence of light or oxygen and has a carotenoid structure.

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