STIGMATELLIN, A NEW ANTIBIOTIC FROM STIGMATELLA AURANTIACA (MYXOBACTERALES)

I. PRODUCTION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

Abstract

An antibiotic activity was extracted from the cell mass of the myxobacterium, Stiginatella aurantiaca strain Sg a15. The antibiotic was toxic for yeasts and filamentous fungi, but not for most bacteria. The compound had the molecular formula C₃₀H₄₂O₇, appears to be a new antibiotic, and was named stigmatellin. In addition to stigmatellin, the strain produced relatively large quantities of a second, structurally unrelated antibiotic, a mixture of three myxalamid homologues.