ACTINOPYRONES A, B AND C, NEW PHYSIOLOGICALLY ACTIVE SUBSTANCES I. PRODUCING ORGANISM, FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES

KENICHI YANO; KOUICHI YOKOI; JUNICHI SATO; JUNJI OONO; TADAYUKI KOUDA; YOICHIRO OGAWA; TOSHIAKI NAKASHIMA

doi:10.7164/antibiotics.39.32

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

ACTINOPYRONES A, B AND C, NEW PHYSIOLOGICALLY ACTIVE SUBSTANCES

I. PRODUCING ORGANISM, FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES

KENICHI YANO, KOUICHI YOKOI, JUNICHI SATO, JUNJI OONO, TADAYUKI KOUDA, YOICHIRO OGAWA, TOSHIAKI NAKASHIMA

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JOURNAL FREE ACCESS

1986 Volume 39 Issue 1 Pages 32-37

DOI https://doi.org/10.7164/antibiotics.39.32

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Abstract

A strain of Streptomyces was found to produce new physiologically active substances. The active compounds were purified and separated into three substances named actinopyrones A, B and C. Actinopyrones exhibited coronary vasodilating activities in anesthetized dogs and weakly antimicrobial activities against some Gram-positive bacteria and dermatophytes.

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