The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
K-252a, A POTENT INHIBITOR OF PROTEIN KINASE C FROM MICROBIAL ORIGIN
HIROSHI KASE, KAZUYUKI IWAHASHI, YUZURU MATSUDA
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JOURNAL FREE ACCESS

1986 Volume 39 Issue 8 Pages 1059-1065

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Abstract
K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.
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© Japan Antibiotics Research Association
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