The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
BIOSYNTHESIS OF THE ANTIBIOTIC ACTINORHODIN
ANALYSIS OF BLOCKED MUTANTS OF STREPTOMYCES COELICOLOR
SHERI P. COLE, BRIAN A. M. RUDD, DAVID A. HOPWOOD, CHIN-JER CHANG, HEINZ G. FLOSS
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1987 Volume 40 Issue 3 Pages 340-347

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Abstract
From two types of class V act mutants of Streptomyces coelicolor two monomeric precursors of actinorhodin have been isolated and their structures determined. One is the known antibiotic kalafungin (2) and the other a new compound (6). Their relationship to actinorhodin biosynthesis is discussed.
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© Japan Antibiotics Research Association
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