The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
TOXICITY OF SELECTED TREMORGENIC MYCOTOXINS AND RELATED COMPOUNDS TO SPODOPTERA FRUGIPERDA AND HELIOTHIS ZEA
PATRICK F. DOWDR. J. COLERONALD F. VESONDER
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JOURNAL FREE ACCESS

1988 Volume 41 Issue 12 Pages 1868-1872

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Abstract
A series of tremorgenic mycotoxins and related compounds were tested for oral toxicity to the fall armyworm (Spodoptera frugiperdd) and corn earworm (Heliothis zed) by incorporation of materials into artificial diets and examining mortality and weights after 7 days. Significant mortality to both insect species was caused with dihydroxyaflavinine and roseotoxin B, while significant mortality to H. zea was also caused by penitrem A at 25 ppm. After 7 days, weights of larvae treated with 25 ppm penitrem A, roseotoxin B, and verruculogen were less than 50% of controls for both insect species. Weights of H. zea larvae treated with 25 ppb of penitrem A were less than 50% those of control larvae. Relative toxicities of the tremorgens and related compounds to insects compared to vertebrates are discussed.
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© Japan Antibiotics Research Association
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