PLACETINS, PLATELET AGGREGATION INHIBITORS FROM STREPTOMYCES SP. Q-1043 I. FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES

TERUAKI OZASA; KENICHI SUZUKI; TOSHIMITSU YAMADA; KIYOSHI SUZAKI; CHIEKO NOHARA; MASATO KOBORI; TAKESHI SAITO

doi:10.7164/antibiotics.43.331

PLACETINS, PLATELET AGGREGATION INHIBITORS FROM STREPTOMYCES SP. Q-1043

I. FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES

TERUAKI OZASA, KENICHI SUZUKI, TOSHIMITSU YAMADA, KIYOSHI SUZAKI, CHIEKO NOHARA, MASATO KOBORI, TAKESHI SAITO

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JOURNAL FREE ACCESS

1990 Volume 43 Issue 4 Pages 331-335

DOI https://doi.org/10.7164/antibiotics.43.331

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Abstract

Placetins, platelet aggregation inhibitors were obtained from the culture broth of Streptomyces sp. Q-1043. These were designated placetins A, Al, B and Bl, respectively. Placetins A and B showed strong cytotoxicities against P388, L1210 and HeLa cells.

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