STUDIES ON NEW DEHYDROPEPTIDASE INHIBITORS IV. CHEMICAL TRANSFORMATION OF WS1358 COMPOUNDS AND AN IMPROVED SYNTHESIS OF WS1358A1

ITSUO UCHIDA; SEIJI HASHIMOTO; TOSHIRO IWAMOTO; SHIGEHIRO TAKASE; MASASHI HASHIMOTO

doi:10.7164/antibiotics.43.344

STUDIES ON NEW DEHYDROPEPTIDASE INHIBITORS

IV. CHEMICAL TRANSFORMATION OF WS1358 COMPOUNDS AND AN IMPROVED SYNTHESIS OF WS1358A1

ITSUO UCHIDA, SEIJI HASHIMOTO, TOSHIRO IWAMOTO, SHIGEHIRO TAKASE, MASASHI HASHIMOTO

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JOURNAL FREE ACCESS

1990 Volume 43 Issue 4 Pages 344-351

DOI https://doi.org/10.7164/antibiotics.43.344

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Abstract

The structures of compounds 3 (and 4) and 5 (and 6) derived from the natural products WS1358A1 (1) (and Bl (2)) have been determined by their spectroscopic evidence. By taking advantage of these transformations, an improved synthesis of Al (1, racemate) has been achieved.

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