The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
TRICHOMYCIN B, A POLYENE MACROLIDE FROM STREPTOMYCES
TADAAKI KOMORI
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1990 Volume 43 Issue 7 Pages 778-782

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Abstract

Two polyene macrolide, trichomycins A and B, were compared by physico-chemical and microbiological methods. The two antibiotics were found to have the same molecular formula, C58H84N2O18 (MW 1, 096), by elemental analysis and FAB-MS. However, 1H and 13C NMR spectrometry studies indicated that the hydroxyl at C-5 of trichomycin A located on C-9 in trichomycin B.
Trichomycin B possessed lower activities against fungi and yeasts than those of trichomycin A.

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