THIAZOCINS, NEW ALDOSE REDUCTASE INHIBITORS FROM Actinosynnema sp. 1. FERMENTATION, ISOLATION AND CHARACTERIZATION

TERUAKI OZASA; TAKASHI YONEDA; MARI HIRASAWA; KENICHI SUZUKI; KOICHI TANAKA; SHIGENOBU KADOTA; MASARU IWANAMI

doi:10.7164/antibiotics.44.768

THIAZOCINS, NEW ALDOSE REDUCTASE INHIBITORS FROM Actinosynnema sp.

1. FERMENTATION, ISOLATION AND CHARACTERIZATION

TERUAKI OZASA, TAKASHI YONEDA, MARI HIRASAWA, KENICHI SUZUKI, KOICHI TANAKA, SHIGENOBU KADOTA, MASARU IWANAMI

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JOURNAL FREE ACCESS

1991 Volume 44 Issue 7 Pages 768-773

DOI https://doi.org/10.7164/antibiotics.44.768

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Abstract

New antibiotics designated as thiazocins A and B were isolated from the culture broth of Actinosynnema sp. C-304. Thiazocins A and B exhibited inhibitory activities against an aldose reductase from human placenta.

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