OLIGOMYCIN F, A NEW IMMUNOSUPPRESSIVE HOMOLOGUE OF OLIGOMYCIN A

HARTMUT LAATSCH; MICHAEL KELLNER; GERHARD WOLF; YONG-SE LEE; FRITZ HANSSKE; SILVIA KONETSCHNY-RAPP; ULRICH PESSARA; WERNER SCHEUER; HUBERTUS STOCKINGER

doi:10.7164/antibiotics.46.1334

HARTMUT LAATSCH, MICHAEL KELLNER, GERHARD WOLF, YONG-SE LEE, FRITZ HANSSKE, SILVIA KONETSCHNY-RAPP, ULRICH PESSARA, WERNER SCHEUER, HUBERTUS STOCKINGER

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JOURNAL FREE ACCESS

1993 Volume 46 Issue 9 Pages 1334-1341

DOI https://doi.org/10.7164/antibiotics.46.1334

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Abstract

Oligomycin F, a new homologue of oligomycin A (1), was isolated from a Streptomyces species and structure 2 was deduced by NMR methods. Compound 2 is highly active against plant pathogenic fungi and is an extremely potent suppressive agent for various immunological systems.

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