The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
Chivosazol A, a New Inhibitor of Eukaryotic Organisms Isolated from Myxobacteria
HERBERT IRSCHIK, ROLF JANSEN, KLAUS GERTH, GERHARD HÖFLE, HANS REICHENBACH
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JOURNAL FREE ACCESS

1995 Volume 48 Issue 9 Pages 962-966

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Abstract
A new antibiotic, chivosazol, was isolated from the culture broth of the myxobacterium Sorangium cellulosum strain So eel2. It is a macrocyclic ring with one oxazol ring and a glycosidically bound 6-deoxyglucose (quinovose) at C-11. The antibiotic shows antimicrobial activity against yeasts and filamentous fungi, and is especially potent against mammalian cells. It was not active against bacteria.
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© Japan Antibiotics Research Association
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