Antibiotics A21459 A and B, New Inhibitors of Bacterial Protein Synthesis I. Taxonomy, Isolation and Characterization

E. SELVA; L. GASTALDO; G. S. SADDLER; G. TOPPO; P. FERRARI; G. CARNITI; B. P. GOLDSTEIN

doi:10.7164/antibiotics.49.145

Antibiotics A21459 A and B, New Inhibitors of Bacterial Protein Synthesis

I. Taxonomy, Isolation and Characterization

E. SELVA, L. GASTALDO, G. S. SADDLER, G. TOPPO, P. FERRARI, G. CARNITI, B. P. GOLDSTEIN

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JOURNAL FREE ACCESS

1996 Volume 49 Issue 2 Pages 145-149

DOI https://doi.org/10.7164/antibiotics.49.145

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Abstract

Novel cyclic peptide antibiotics A21459 A and B are produced by a member of the genus Actinoplanes sp. These antibiotics inhibit bacterial protein synthesis and have selective antimicrobial activity against clostridia, mycoplasma and some Gram-negative bacteria.

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