Bioxanthracenes from the Insect Pathogenic Fungus Cordyceps pseudomilitaris BCC 1620 I. Taxonomy, Fermentation, Isolation and Antimalarial Activity

AMONLAYA JATURAPAT; MASAHIKO ISAKA; NIGEL L. HYWEL-JONES; YUWAPIN LERTWERAWAT; SUMALEE KAMCHONWONGPAISAN; KANYAWIM KIRTIKARA; MORAKOT TANTICHAROEN; YODHATHAI THEBTARANONTH

doi:10.7164/antibiotics.54.29

Bioxanthracenes from the Insect Pathogenic Fungus Cordyceps pseudomilitaris BCC 1620

I. Taxonomy, Fermentation, Isolation and Antimalarial Activity

AMONLAYA JATURAPAT, MASAHIKO ISAKA, NIGEL L. HYWEL-JONES, YUWAPIN LERTWERAWAT, SUMALEE KAMCHONWONGPAISAN, KANYAWIM KIRTIKARA, MORAKOT TANTICHAROEN, YODHATHAI THEBTARANONTH

Author information

AMONLAYA JATURAPAT
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
MASAHIKO ISAKA
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
NIGEL L. HYWEL-JONES
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
YUWAPIN LERTWERAWAT
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
School of Bioresources and Technology, King Monkot's University of Technology Thonburi
SUMALEE KAMCHONWONGPAISAN
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
KANYAWIM KIRTIKARA
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
MORAKOT TANTICHAROEN
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
School of Bioresources and Technology, King Monkot's University of Technology Thonburi
YODHATHAI THEBTARANONTH
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)
Department of Chemistry, Faculty of Science, Mahidol University

JOURNAL FREE ACCESS

2001 Volume 54 Issue 1 Pages 29-35

DOI https://doi.org/10.7164/antibiotics.54.29

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Abstract

Eleven bioxanthracenes and two monomers, six novel in nature, were isolated from the insect pathogenic fungus Cordyceps pseudomilitaris BCC 1620. Growth optimization of the strain led to the improvement of bioxanthracenes production. The bioxanthracenes were evaluated for their antimalarial activity and cytotoxicity.

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