YM-266183 and YM-266184, Novel Thiopeptide Antibiotics Produced by Bacillus cereus Isolated from a Marine Sponge II. Structure Elucidation

KEN-ICHI SUZUMURA; TAKAKO YOKOI; MASASHI FUNATSU; KOJI NAGAI; KOICHI TANAKA; HUIPING ZHANG; KENICHI SUZUKI

doi:10.7164/antibiotics.56.129

YM-266183 and YM-266184, Novel Thiopeptide Antibiotics Produced by Bacillus cereus Isolated from a Marine Sponge

II. Structure Elucidation

KEN-ICHI SUZUMURA, TAKAKO YOKOI, MASASHI FUNATSU, KOJI NAGAI, KOICHI TANAKA, HUIPING ZHANG, KENICHI SUZUKI

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JOURNAL FREE ACCESS

2003 Volume 56 Issue 2 Pages 129-134

DOI https://doi.org/10.7164/antibiotics.56.129

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Abstract

YM-266183 and YM-266184 are new antibacterial substances that have activity against drug-resistant bacteria produced by Bacillus cereus QN03323. These structures were elucidated by MS and NMR spectral analysis. YM-266183 and YM-266184 are the cyclic thiopeptides containing thiazole and pyridine moieties, and several unusual amino acids.

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