ISOLATION-RATE OF PSEUDOMONAS AERUGINOSA FROM CLINICAL MATERIALS AND ITS SUSCEPTIBILITY TO ANTIBIOTICS

Abstract

We studied on the isolation rate of Pseudomonas aeruginosa from various clinical materials and the susceptibility of this bacteria to several kinds of antibiotics during recent ten years.
The isolation rate of Pseudomonas aeruginosa from clinical materials are 11-17% and almost constant during these ten years, but there is a tendency to increase the rate gradually since 1965. The isolation rate from pus and secretes of surgery and gynecology are increasing year by year.
Pseudomonas aeruginosa is very sensitive to CL, PL-B and GM, and the minimum inhibitory concentrations are below 12.5 mcg/ml, but a few strains are resistant to 100mcg/ml of GM.
There are many resistant strains to SM, KM, CP or TC, and almost all strains are resistant to 400 mcg/ml of CER, LCM or AB-PC. The susceptibility to rifampicin is between 50 and 12.5mcg/ml.
To CB-PC is the minimum inhibitory concentration of many strains between 25-50mcg/ml, but 8.7% of all strains are resistant to 400mcg/ml.
There are no remarkable changes of susceptibility to SM, KM and CL from 1963 to 1970.