The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
A CASE OF FISH TAPEWORM INFECTION TREATED WITH PAROMOMYCIN AND AN OBSERVATION ON ITS MODE OF ACTIVITY
YUTAKA KANAZAWA
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1971 Volume 24 Issue 3 Pages 143-145

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Abstract

A male adult suffering from fish tapeworm infection despite past treatment was successfully treated with a single dose of 4,000mg paromomycin.
The drug concentrations in head or in segments of the worm removed were as high as 240μg/ml or more.
Consequently, it was presumed that some acute toxic effect of paromomycin, which was well absorbed into parasite, but ill-absorbed from the gastrointestinal tract of human, is one of the mode ofantihelminthic activity, in this case.

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