1971 Volume 24 Issue 3 Pages 143-145
A male adult suffering from fish tapeworm infection despite past treatment was successfully treated with a single dose of 4,000mg paromomycin.
The drug concentrations in head or in segments of the worm removed were as high as 240μg/ml or more.
Consequently, it was presumed that some acute toxic effect of paromomycin, which was well absorbed into parasite, but ill-absorbed from the gastrointestinal tract of human, is one of the mode ofantihelminthic activity, in this case.