The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
THERAPEUTIC EFFECT OF CEPHAPIRIN IN SURGICAL BILIARY INFLAMMATORY DISEASES
TAKEHARU HISATSUGUTEIJI FURUSAWAHIROSHI YAMAMOTOMASAYA NISHIMURAHIDEHIKO SHIMURA
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1974 Volume 27 Issue 2 Pages 185-188

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Abstract
Cephapirin was given by intramuscular injection, 2 g per day, dissolved in sterile water or lidocaine hydrochloride solution, to 19 patients with inflammatory biliary tract disease and 5 patients with gastric cancer, intussusception, retroperitoneal cyst, appendicitis and tumor of the thyroid gland. The results in 19 cases of the biliary tract diseases were good in 14 cases (73.7%), fair in 1 and unchanged in 4, in 5 cases of non-biliary-tract diseases, good in 3, fair in 1 and undecided in 1.
Bacteriolozical examination was carried out on 18 cases. In 11 cases, cultures were positive for Escherkhlac oil, F romm, Pseudomonaas eruginosa, E nterobacteriaceae, A kaligenesf a ecalis, Enterococcus and Staphylococcuse pidermidisi n bile as simple or mixed infection.
No side effect was observed in all cases except localized pain by the intramuscular injection.
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© Japan Antibiotics Research Association
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