Abstract
Cephapirin was given by intramuscular injection, 2 g per day, dissolved in sterile water or lidocaine hydrochloride solution, to 19 patients with inflammatory biliary tract disease and 5 patients with gastric cancer, intussusception, retroperitoneal cyst, appendicitis and tumor of the thyroid gland. The results in 19 cases of the biliary tract diseases were good in 14 cases (73.7%), fair in 1 and unchanged in 4, in 5 cases of non-biliary-tract diseases, good in 3, fair in 1 and undecided in 1.
Bacteriolozical examination was carried out on 18 cases. In 11 cases, cultures were positive for Escherkhlac oil, F romm, Pseudomonaas eruginosa, E nterobacteriaceae, A kaligenesf a ecalis, Enterococcus and Staphylococcuse pidermidisi n bile as simple or mixed infection.
No side effect was observed in all cases except localized pain by the intramuscular injection.