Abstract
Studies were performed in 8 patients with osteoatticular infections to examine the concentrations of sulbenicillin in the venous blood and exudate following administration and the concentrations of the antibiotic in the exudate when serratiopeptidase was orally administered concomitantly with the antibiotic. The results of the examination indieated that the transfer of sulbenicillin into the exudate tended to increase when 30mg/day of serratiopeptidase was concomitantly given for 6 days, though further examination was thought necessary by increasing number of subjects and elaborating on the methodology.
