CLINICAL EVALUATION OF CEFOXITIN AGAINST INTRACTABLE BRONCHOPULMONARY INFECTIONS

PATIENTS NOT RESPONDING TO OTHER CONVENTIONAL ANTIBIOTICS

Abstract

Cefoxitin was administered to a total of 17 patients with intractable bronchopulmonary infections who had failed to respond to other conventional antibiotics, and the following results were obtained.
(1) The clinical response, except 1 patient classified as evaluation impossible, was excellent in3 patients, good in 10 and fair in 3 with an efficacy rate of 81.3%.
(2) An improvement rate of more than70% was observed in the findings of body temperature, dyspnea, colour of sputum, WBC and CRP.
(3) There was no subjective nor objective side effects attributable to cefoxitin.
In view of the results stated above, we have concluded thatcefoxitin is a useful antibiotic for the treatment of intractable bronchopulmonary infections