ACUTE AND SUBACUTE TOXICITY STUDIES ON NETILMICIN

Abstract

An acute toxicity study on netilmidn (NTL) and gentamicin (GM) was carried out in mice and rats, subacute toxicity of NTL was tested in comparison with GM in Sprague-Dawley (SD) rats. The ariimals were treated with NTL (12.5, 25, 50 and 100 mg/kg/day) or GM (50 and 100 mg/kg/day) intramuscularly for 30 days and followed by 35-day recovery test without treatment.
The following results were obtained.