Abstract
Cefoxitin (CFX) was administrated to a total of 12 hospitalized patients with digestive diseases, in combination with aminoglycosides.
The following results were obtained:
1. Clinical effects of CFX on 12 cases were “excellent” in 4 cases, “good” in 5, “fair” in 1 and “unknown” in 2, with the efficacy rate of 75%.
2. All 4 cases who developed septicemia with underlying severe diseases showed “excellent” effect to CFX.
3. Clinical results of 8 cases with hepatic biliary tract infections were “good” in 5, “fair” in 1 and “unknown” in 2, with the efficacy rate in 62.5%.
4. As for side effects, an allergic reaction was observed in 1 case, and it is suggested renal function should be monitored carefully in a case of combination use with aminoglycosides.
