The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
IMIPENEM/CILASTATIN SODIUM IN THE TREATMENT OF OBSTETRIC AND GYNECOLOGIC INFECTIONS
FUMIO DOKO
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1986 Volume 39 Issue 5 Pages 1427-1431

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Abstract
Imipenem/cilastatin sodium (MK-0787/MK-0791), a carbapenem antibiotic and a dehydropeptidase-I inhibitor, was administered at a dose of 500mg/500mg twice a day for 5 days for the treatment of obstetric and gynecologic infections.
A total of 10 patients was evaluated, and the clinical results were rated as excellent in 1, good in 7 and poor in 2 patients.
As a side effect, rash was observed in 1 patient but it disappeared by the third day after the treatment was discontinued.
No abnormal laboratory findings were observed in our study.
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© Japan Antibiotics Research Association
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