Imipenem/Cilastatin sodiumの産婦人科感染症に対する効果

岩城 雅範; 佐藤 博; 牧野田 知; 出店 正隆; 田畑 雅章; 山口 辰美; 高岡 波留人; 新開 奈保子; 大久保 仁; 佐藤 春美; 桜木 範明; 宇野 洋一; 関 敏雄; 藤本 征一郎; 一戸 喜兵衛

doi:10.11553/antibiotics1968b.39.1509

CLINICAL EVALUATION OF IMIPENEM/CILASTATIN SODIUM IN GYNECOLOGICAL INFECTION

MASANORI IWAKI, HIROSHI SATO, SATORU MAKINODA, MASATAKA DEMISE, MASAAKI TABATA, TATSUMI YAMAGUCHI, HARUTO TAKAOKA, NAOKO SHINKAI, HITOSHI OKUBO, HARUMI SATO, NORIAKI SAKURAGI, YOUICHI UNO, TOSHIO SEKI, SEIICHIROU FUJIMOTO, KIHYOE ICHINOE

Author information

MASANORI IWAKI
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
HIROSHI SATO
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
SATORU MAKINODA
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
MASATAKA DEMISE
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
MASAAKI TABATA
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
TATSUMI YAMAGUCHI
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
HARUTO TAKAOKA
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
NAOKO SHINKAI
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
HITOSHI OKUBO
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
HARUMI SATO
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
NORIAKI SAKURAGI
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
YOUICHI UNO
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
TOSHIO SEKI
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
SEIICHIROU FUJIMOTO
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
KIHYOE ICHINOE
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine

JOURNAL FREE ACCESS

1986 Volume 39 Issue 6 Pages 1509-1513

DOI https://doi.org/10.11553/antibiotics1968b.39.1509

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Abstract

The MK-0787/MK-0791 is a combination of imipenem (a carbapenem antibiotic) and cilastatin sodium (a dehydro peptidase-I inhibitor) in a 1 to 1 ratio, which produces a higher urinary recovery of imipenem than imipenem alone.
The MK-0787/MK-0791 was used in 8 female patients with intrapelvic infections.
Clinical efficacies were very good in all the patients.
There were neither subjective nor objective side effects nor abnormal laboratory findings.

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