The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
EXPERIENCES WITH SULTAMICILLIN GRANULES IN PEDIATRIC PATIENTS
KOSEI IGUCHI, HITOSHI KAMIYA, MINORU SAKURAI, SHIN SHIMIZU, HIDEAKI NISHI, HIROSHI KAWAGUCHI, TAMOTSU YOSHIZUMI, MASAKAZU INOUE, MASAMITSU KOJIMA
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1988 Volume 41 Issue 12 Pages 1906-1913

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Abstract
Sultamicillin (SBTPC) is a combination drug of sulbactam (SBT) and ampicillin (ABPC) in an ester bonding at 1:1 ratio.
SBT, a new semisynthetic β-lactamase inhibitor restores and extends the spectrum of ABPC against resistant strains of bacteria.
SBTPC granules were administrated to 26 pediatric patients with infections, and clinical efficacies were studied in 23 patients.
The clinical efficacy rate was 95.7% and the drug was evaluated to be highly effective for the treatment of infectious diseases in the pediatric field. SBTPC was safe and well tolerated.
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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series B

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