The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
CLINICAL STUDIES ON CEFTIBUTEN IN THE URINARY FIELD INFECTION
KEIZO SUZUKIYOSHIHIRO NAGATAMASAKI HORIBA
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1990 Volume 43 Issue 11 Pages 2003-2010

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Abstract

Efficacies of ceftibuten (CETB, 7432-S, 200 mg/capsule) in urinary tract infections (UTI) were studied. The results of the study are summarized as described below.
1. CETB was administered to 15 complicated chronic cases of UTI using a dose level of 400 mg per day. The efficacy rates determined according to the criteria prescribed by the UTI committee and according to physicians' judgements were 81.8% and 92.3%, respectively.
Bacteriological efficacy rates were 100% against Gram-negative rods and 87.5% against Grampositive cocci
2. Only 1 cace of adverse reaction, slight dizziness, was noted.
3. CETB appears to be the most useful agent of the new oral cephems against strains of Serratia marcescens which are resistant to new quinolones.

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© Japan Antibiotics Research Association
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