Abstract
We have evaluated the effectiveness and safety of norfloxacin (NFLX) in 18 children with infectious diseases.
Doses ranging from 5.6 to 18.8 mg/kg/day for t. i. d. or q. i. d. were used.
The causative bacteria were Campylobacter jejuni in 3 cases, Salmonella typhimurium in 1, Staphylococcus aureus in 2, Haemophilus infiuenzae in 1 and unknown in 11 cases.
Except 1 strain of S. aureus, all the bacteria mentioned above were eradicated.
Clinical effects were excellent in 8, good in 8, poor in 2, and the total efficacy rate was88.9%.
No side effects nor abnormal laboratory test results were observed.
These results have shown that the NFLX is a usefull drug for infectious diseases in the pediatric field.
