CLINICAL STUDIES OF S-1108 FINE GRANULES IN PEDIATRICS
1993 Volume 46 Issue 12 Pages 1107-1113
Details
1993 Volume 46 Issue 12 Pages 1107-1113
We have evaluated S-1108 fine granules for therapeutic effectiveness in children. The results are summarized as follows.
1. A clinical study was performed with 16 children with infections, including 8 with acute tonsillitis, 3 with acute pharyngitis, 2 with scarlet fever, 1 each with acute bronchitis, pertussis and urinary tract infection.
Doses ranging from 8.8 to 10.6mg/kg body weights were given in 3 divided portions. Durations of treatment ranged from 2 to 15 days.
The therapeutic responses were considered “excellent” in 1 and “good” in 13, with an efficacy rate of 87.5%, and the bacteriological eradication rate was 91%.
2. No adverse reactions were observed. In laboratory tests, eosinophilia was observed in one patient.
It was concluded the S-1108 was promising drug for the treatment of bacterial infections in children.
