BACTERIA ISOLATED FROM SURGICAL INFECTIONS AND ITS SUSCEPTIBILITIES TO ANTIMICROBIAL AGENTS

SPECIAL REFERENCES TO BACTERIA ISOLATED BETWEEN JULY 1994 AND JUNE 1995

Abstract

Isolated bacteria from infections in general surgery during the period from July 1994 to June 1995 were investigated by a multicenter study in Japan, and the following results were obtained.
One hundred and fifty-three strains were isolated from primary infections, and 143 stra ins were isolated from postoperative infections. From primary infections, both anaerobic Gram-positive and negative bacteria were predominant, and from postoperative infections, aerobic Gram-positive bacteria were predominant. Among aerobic Gram-positive bacteria, the isolation rate of Enterococcus faecalis was highest, followed by that of Staphylococcus aureus from both types of infections. Among anaerobic Gram-positive bacteria, the isolation rate of Streptococcus intermedius was highest from primary infections, but from postoperative infections anaerobic Gram-positive bacteria was uncommon. Among aerobic Gram-negative bacteria, Escherichia coli was most predominantly isolated from primary infections, followed by Klebsiella pneumoniae and Pseudomonas aeruginosa in this order. From postoperative infections, P.aeruginosa was most predominantly isolated, followedby Serratia marcescens and E. coli. Among anaerobic Gram-negative bacteria, the isolation rate of Bacteroides fragilis group was the highest from both types of infections.
We have noticed that resistant strains against imipenem and ofloxacin were increasing among P. aeruginosa and resistant strains against cefazolin were incresing among E. coli. MICs of cefazolin against four out of 30 strains of E. coli were higher than 100μg/ml, and MICs of imipenem was higher than 50μg/ml against 5 out of 22 strains of P.aeruginosa.