BACTERIA ISOLATED FROM SURGICAL INFECTIONS AND ITS SUSCEPTIBILITIES TO ANTIMICROBIAL AGENTS

SPECIAL REFERENCES TO BACTERIA ISOLATED BETWEEN APRIL 2002 AND MARCH 2003

Abstract

Tendency of isolated bacteria from infections in general surgery during the periodfrom April 2002 to March 2003 were investigated in a multicenter study in Japan, and the following results were obtained.
In this series, 334 strains were isolated from 131 (75.3%) of 174 patients with surgical infections. One hundred and seventy-one strains were isolated from primary infections, and 163 strains were isolated from postoperative infections. From primary infections, anaerobic Gram-positive bacteria were predominant, while aerobic Gram-positive bacteria were predominant from postoperative infections. Among aerobic Gram-positive bacteria, although the isolation rate of Staphylococcus aureus was the highest, followed by that of Enterococcus faecalis from primary infections, the isolation rate of E. faecalis was the highest from postoperative infections. Among anaerobic Gram-positiveb acteria, t he isolationr ate of Peptostreptococcus spp.was the highest fromb oth types of infections. Among aerobic Gram-negative bacteria, Escherichia coli was the most predominantly isolated from primary infections, followed by Klebsiella pneumoniae and Pseudomonas aeruginosa in this order, and from postoperative infections, E. coli was the most predominantly isolated, followed by P.aeruginosa, Enterobacter cloacae, and Citobacter freundii. Among anaerobic Gram-negative bacteria, the isolation rate of Bacteroides fragilis group was the highest from both types of infections. The isolation rate of aerobic Gram-negative bacteria from primary infections and that of aerobic Gram-positive bacteria from postoperative infections were high in the last several years. We noticedn o vancomycin-resistanGt ram-positivec occi nor P. aeruginosa producingm etallo-β-lactamase. But we noticedc efazolin-resistant E. coli probablyp roducing extendeds pectrum β-lactamase.