A New Antibiotic, Tubercidin

Abstract

In the course of searching new antibiotics active against tubercle bacilli, a new antibiotic, named tubercidin, was obtained in the crystalline form from the broth of an unidentified actinomyces strain which was isolated from the soil of Chiba Prefecture. This antibiotic also showed a strong antitumor action in vitro, using NF mouse sarcoma. The present paper deals with its isolation, purification and physical and chemical properties as well as its biological activity.