Archivum histologicum japonicum
Print ISSN : 0004-0681
Histological Observations on the Adrenal Gland of the Chick after Injection of Insulin and Adrenalin
Ikuo KUNISHIMA
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1960 Volume 21 Issue 1 Pages 129-145

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Abstract
The histological changes of adrenal glands of chicks at 1-6 hours after one time intramuscular injection of 0.5 i. u. insulin or 0.2mg adrenalin were observed.
1. In the domestic fowl, it is impossible to differentiate three zones of the adrenal cortex as in the mammal, because the cortical tissue is distributed throughout the gland in the form of irregularly arranged columns.
2. No stainable glycogen was observed in the adrenal cortex of the domestic fowl.
3. After injection of insulin, following changes were produced: increase in nuclear volume of the cortical cell (1-4 hours after injection), transitory decrease (1-2 hours) and following slight increase (4 hours) of sudanophilic substances, decrease of ascorbic acid in the cortical tissue (1-6 hours), transitory enlargement (1 hour) and following reduction (2-4 hours) in nuclear volume of the medullary cell and enlargement of the sinusoidal capillary lumen (1-4 hours).
4. After injection of adrenalin, following changes were produced: transitory reduction (1 hour) and following enlargement (4 hours) of the nuclear volume of the cortical cell, decrease of sudanophilic substances in the cortical tissue (1-6 hours), decrease of ascorbic acid (1-6 hours), decrease of ascorbic acid (1-6 hours), transitory reduction (1 hour) and following enlargement (2-6 hours) of the nuclear volume of the medullary cell and enlargement of the sinusoidal capillary lumen.
5. It was clarified that the adrenal gland of the domestic fowl which had been considered to be strongly resistant to the stress, showed clear reaction in the histological figure to one time injection of insulin or adrenalin.
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